Cyclin D1, RET and p27 Expression in Papillary Thyroid Microcarcinoma
نویسندگان
چکیده
منابع مشابه
Cyclin D1, Ret and P27 Expression in Papillary Thyroid Microcarcinoma
Th e aim of the study was to determine the influence of RET, p27 and cyclin D1 on regional lymph node metastases in papillary microcarcinoma. The analysis included 70 patients with papillary thyroid microcarcinoma that underwent surgery at Split University Hospital Center between 1999 and 2001. Immunohistochemistry was performed on formalin-fixed, paraffin-embedded tissue by the RET, p27 and cy...
متن کاملCyclin D1 and p27 expression as prognostic factor in papillary carcinoma of thyroid: association with clinicopathological parameters.
AIM To determine the prognostic value of cell cycle regulators cyclin D1 and p27 for papillary thyroid carcinomas. METHODS Analysis included 180 patients with papillary thyroid carcinoma who underwent surgery at Split University Hospital Center between 1999 and 2001. Clinical data were obtained from clinical charts and histopathology reports. Immunohistochemistry was performed on formalin-fix...
متن کاملCyclin D1 expression in primary thyroid carcinomas.
OBJECTIVES The aim of the study was to demonstrate and evaluate the expression of cyclin D1, a protein connected with a cell cycle, by means of the immunohistochemical method in malignant thyroid neoplasms. The purpose of the analysis of the results was to explain the relation between cyclin D1 in thyroid cells and neoplasm transformation. MATERIAL AND METHODS The study was conducted on thyro...
متن کاملTreatment for papillary thyroid microcarcinoma
AIM OF THE STUDY The treatment for papillary thyroid microcarcinoma (PTMC), which is a tumor measuring less than 1 cm, is still a subject of controversy. The aim of this study is to retrospectively evaluate the patients diagnosed with PTMC in terms of their clinical and histopathological features. MATERIAL AND METHODS A total of 153 consecutive patients with PTMC were treated, and their clini...
متن کاملComparative analysis of gene expression profiles of papillary thyroid microcarcinoma and papillary thyroid carcinoma.
PURPOSE Papillary thyroid carcinomas (PTCs) measuring 1.0 cm or less were separately defined as papillary thyroid microcarcinomas (PTMs) by the World Health Organization, emphasizing on their benign behavior. However, some reported that PTMs may have aggressive behavior, can cause regional, or even distant metastases. But till now, the characteristics of PTMs were only reviewed and described by...
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ژورنال
عنوان ژورنال: ACTA CLINICA CROATICA
سال: 2017
ISSN: 0353-9466
DOI: 10.20471/acc.2017.56.01.03